Venlafaxine withdrawal (this is me very well stated)

[steve2470]

10. Venlafaxine and Serious Withdrawal Symptoms: Warning to Drivers

https://www.medscape.com/viewarticle/506427

Abstract
Venlafaxine is a widely used serotonin- and norepinephrine-reuptake inhibitor-type antidepressant that causes serious adverse effects in at least 5% of cases. Serious withdrawal symptoms may occur within hours of cessation or reduction of the usual dosage and may affect motor and coordination skills to such a degree that patients should be explicitly urged either to adhere to a strict medication routine or not to drive a car. Recent clinical evidence about withdrawal symptoms is presented that may indicate incidents in noradrenergic activity irrespective of dosage.

Keywords: Venlafaxine, withdrawal, discontinuance syndrome, serotonin, adrenaline, seizures, drivers.

Objective: To present clinical information and a brief review of severe venlafaxine withdrawal symptoms that may occur within hours after cessation and affect the ability to drive a motor vehicle or use heavy or dangerous machinery.

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Serotonin, Noradrenaline Withdrawal
Venlafaxine hydrochloride (Effexor, Dobupal) is a phenylethylamine-derivative antidepressant and anxiolytic agent that acts as a serotonin- and noradrenaline-reuptake inhibitor (SNRI). It is used primarily in major depressive disorder, with labeled uses including generalized anxiety disorder and social phobia. Nonlabeled uses include depressive symptom remission, obsessive-compulsive disorder, and chronic pain syndromes.