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mitch96

(15,190 posts)
3. The science with references... This MD reads all the med science and comments...
Sun Nov 20, 2022, 11:09 AM
Nov 2022
https://nutritionfacts.org/2022/11/15/does-smoking-cannabis-cause-lung-cancer/

The key takeaways:
At least 33 carcinogens are in marijuana smoke, including polycyclic aromatic hydrocarbons that are also found in grilled meat.

Most cigarette users inhale more smoke each day than do marijuana smokers, but cannabis users may inhale more deeply and hold in smoke longer, which can result in depositing four times more tar into their lungs.

When cigarette use was accounted for, no increased cancer risk was found and the same was found for head and neck cancer.

Regular marijuana use leads to symptoms of chronic bronchitis, but there is no evidence of emphysema (long-term lung damage) or increased risk of lung cancer.

Smoking one joint a day for ten years may only translate to six months of smoking a pack of cigarettes a day, and, in most studies on tobacco smoke and lung cancer, six months of smoking in a lifetime may even classify you as a “never smoker.”

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Institute of Medicine (US) and National Research Council (US) National Cancer Policy Board. State programs can reduce tobacco use. Washington, DC: National Academies Press (US); 2000.
Tashkin DP. Effects of marijuana smoking on the lung. Ann Am Thorac Soc. 2013;10(3):239-247.
Bloor RN, Wang TS, Spanel P, Smith D. Ammonia release from heated 'street' cannabis leaf and its potential toxic effects on cannabis users. Addiction. 2008;103(10):1671-1677.
Hoffmann D, Brunnemann KD, Gori GB, Wynder EL. On the carcinogenicity of marijuana smoke. In: Runeckles V.C. (eds) Recent Advances in Phytochemistry. Boston, MA: Springer; 1975;63-81.
Hashibe M, Morgenstern H, Cui Y, et al. Marijuana use and the risk of lung and upper aerodigestive tract cancers: results of a population-based case-control study. Cancer Epidemiol Biomarkers Prev. 2006;15(10):1829-1834.
Huang YH, Zhang ZF, Tashkin DP, Feng B, Straif K, Hashibe M. An epidemiologic review of marijuana and cancer: an update. Cancer Epidemiol Biomarkers Prev. 2015;24(1):15-31.
Munson AE, Harris LS, Friedman MA, Dewey WL, Carchman RA. Antineoplastic activity of cannabinoids. J Natl Cancer Inst. 1975;55(3):597-602.
Maida V, Daeninck PJ. A user's guide to cannabinoid therapies in oncology. Curr Oncol. 2016;23(6):398-406.
Guzmán M, Duarte MJ, Blázquez C, et al. A pilot clinical study of Delta9-tetrahydrocannabinol in patients with recurrent glioblastoma multiforme. Br J Cancer. 2006;95(2):197-203.



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