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NNadir

(35,021 posts)
5. This is decidedly true. This test is only in a very preliminary phase...
Thu Mar 16, 2023, 07:53 AM
Mar 2023

...in this case, as the authors make clear.

Given the expected false discovery rate that one can expect, it should be considered only for screening purposes and be subject to confirmatory testing.

Notably, it only covers, even if subject ultimately to regulatory approval, a stage to which it will advance if the development pans out, triple negative, and not the other types of breast cancer.

It should prove useful for preparing surgeons and pathologists for what they may see on biopsy and tumor morphology.

This test depends on access, at least for now, on high resolution mass spectrometry, expensive instruments, but almost certainly can be moved to less expensive and more available (in CLIA labs) triple quad mass specs if it is fully validated.

It's a lead, not a result. For now everyone should do what is confirmed to work best, including self examination.

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